C. trachomatis infection can be effectively cured with antibiotics.
Guidelines recommend azithromycin, doxycycline, erythromycin, levofloxacin or ofloxacin.
In men, doxycycline (100 mg twice a day for 7 days) is probably more effective than azithromycin (1 g single dose) but evidence for the relative effectiveness of antibiotics in women is very uncertain.
Agents recommended during pregnancy include erythromycin or amoxicillin.
Tetracycline is the most preferred antibiotic to treat C.trachomatis and has the highest success rate.
Erythromycin is less preferred as it may cause gastrointestinal side effects, which can lead to non-adherence.
If treatment is necessary during pregnancy, levofloxacin, ofloxacin, tetracycline, and doxycycline are not prescribed.
In the case of a patient who is pregnant, the medications typically prescribed are azithromycin, amoxicillin, and erythromycin.
See also: How to treat Cytomegalovirus infection?